US biotech Verve Therapeutics is looking to discover and develop gene editing therapies, based on technologies such as CRISPR, to replace statins and reduce the risk of heart disease. Based in Cambridge, Massachusetts, Verve has secured $58.5 million in Series A financing in a round led by GV (Google Ventures), with Arch Venture Partners, F-Prime
Researchers in UK, Spain and Austria have found that a genetic test can successfully predict whether chemotherapy would be beneficial for patients with the most common type of breast cancer, oestrogen-receptor positive, HER2-negative. The test could help to highlight patients with a high-risk of metastasis to chemotherapy, while allowing lower-risk patients to opt out of
The bacterium, Porphyromonas gingivalis, which is involved in periodontitis, the most serious form of gum disease. These new findings underscore the importance of good dental hygiene as scientists seek ways to better control this common bacterial infection. “Oral hygiene is very important throughout our life, not only for having a beautiful smile but also to decrease
Scientists have developed and tested a vaccine that they say could be used to treat chronic pain caused by osteoarthritis. In a collaboration by the Jenner Institute and the Kennedy Institute of Rheumatology at the University of Oxford, researchers have developed a virus-like particle vaccine able to trigger the immune system to produce antibodies to
As part of a new project to sequence specific parts of a genome from 50k UK biobanks, new genetic data becomes available to the global health research community. Generated at the Regeneron Genetics Center, the data was gathered as part of a large-scale collaboration between UK Biobank, GSK and Regeneron and according to the latter, it has
Swiss researchers have been studying people with a rare and unusual condition called broken heart syndrome. This weakening and failing of the heart happens suddenly, often after a stressful or emotional event such as bereavement. It is little understood but the work in the European Heart Journal suggests the mind’s response to stress plays a part. Also
A British scientist has developed innovative technology that is able to deliver drugs deep into the brain, which could aid treatment of neurological diseases including Parkinson’s and cancer. The technology was designed by Steven Gill, a professor of neurosurgery at the University of Bristol, and has shown encouraging results in its first controlled clinical trial.
The first map of great whites sharks’ DNA has revealed “mutations” that protect the animals against cancer and other illnesses. Scientists hope that more research could help apply the findings to treating age-related illnesses in humans, as the great white’s ability to repair its own DNA has evolved in ways ours hasn’t. Unstable genes in
The research led by scientists at the MRC Toxicology Unit based in Leister suggests that by analysing levels of DNA in the blood, the early detection of lung cancer could be improved. Published in the journal Disease Models and Mechanisms, the study found that in preliminary tests using mice a blood test could measure the circulating levels
First child with acute lymphoblastic leukaemia (ALL) receives CAR-T therapy on the NHS, treatment to be made available to adult patients.
There has been with two significant developments in the use of CAR-T therapies, marking a historic time for blood cancer treatments, as recent headlines announced that the first child with ALL had successfully received CAR-T therapy on the NHS. CAR-T therapies are a revolutionary treatment that take samples of immune cells from the patient and genetically modify