Servier and Vernalis announce milestones in oncology drug discovery collaboration

Vernalis and Servier’s partnership has been successfully running for 10 years, the collaboration takes advantage of Vernalis’ proprietary fragment and structure-based drug discovery platform, and of Servier’s expertise in medicinal chemistry, cancer biology and pharmacology to bring innovation in oncology one step further. The collaboration focuses on complicated molecular targets, some of which, such as

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Drug delivery system discovered at Oregon State University shows promise for solid tumors

New cancer-drug delivery system shows the ability to exploit oxygen-poor areas of solid tumors that cause the growths to be resistant to standard chemotherapy and radiation treatment. Carcinomas that affect the breast, lung, prostate and colon are among these solid-tumor cancers, as are malignancies in the lymphatic system, known as lymphomas, and the much less

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Mechanism that causes cancer cells to self-destruct discovered by scientist at Tel Aviv University

A Tel Aviv University study published last month in Oncotarget unveils the role of three proteins in killing fast-duplicating cancer cells while they’re dividing. The research led by Prof. Malka Cohen-Armon of TAU’s Sackler School of Medicine, finds that the proteins can be specifically modified during mitosis – to unleash an inherent “death mechanism” that

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Research suggests that diabetes drug could be key to treating aggressive forms of breast cancer

Researchers from the Zhejiang University School of Medicine have identified that the function of metabolic enzyme AKR1B1 is key to the progression of aggressive ‘basal-like’ breast cancer, meaning an existing diabetes drug which inhibits it may be useful in fighting the disease. It was found that AKR1B1 is prevalent at higher levels in basal-like and

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Vaccine shows promising results for early-stage breast cancer patients

Deregulation and inhibition of the immune system contributes to cancer development. Various therapeutic strategies aim to re-stimulate the immune system to recognise cancer cells and target them for destruction. Researchers from Moffitt Cancer Center have recently reported that a dendritic cell vaccine that targets the HER2 protein on breast cancer cells is safe and effectively

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