Boehringer Ingelheim has recently unveiled opnME.com, a centralised platform that allows access to selected pre-clinical molecules from its portfolio for free for non-clinical investigation by international scientists. The German pharmaceutical company hopes that the move will stimulate independent drug discovery and collaborative partnerships worldwide, in addition to the identification of novel treatment solutions for patients.
Since their discovery in 2006, induced pluripotent stem cells provided hope for many diseases. But further research of the complex regulation of pluripotent stem cell identity revealed unexpected difficulties. A team of researchers at the Cluster of Excellence CECAD in Cologne, has now found an efficient way to produce neurons from pluripotent stem cells. As
Previous research has shown that obesity is associated with poorer outcomes from several kinds of cancer, including breast, colon, ovarian, and prostate cancers. New research suggests that excess adiposity can affect the “pharmacokinetics” of chemotherapy, or the way drugs are absorbed, metabolised, and excreted from the body. Steven Mittelman, MD, PhD, Associate Professor of Paediatrics
Approximately one third of drugs sold in the US target G protein-coupled receptors, which are the most utilised cell receptors in the human body, partly as they are uniquely accessible at cell surface level. New mapping conducted by the University of Copenhagen and Uppsala University of all these drugs on the market and currently tested
Research from the Karolinska Institute has suggested that commonly used blood-thinning drugs for reducing stroke risk in patients with atrial fibrillation (AF) suggests that anticoagulants may also protect patients from dementia. Studies had previously pointed towards a link when looking at 444,106 patients with AF’s records to assess if they could find a clear correlation.
Ground breaking Artificial Intelligence System has ability to identify 97% of those at risk of breast cancer
Scientists at MIT’s Computer Science and Artificial Intelligence Laboratory have developed a machine learning AI system that has the ability to diagnose patients with breast cancer 97% of the time. The current screening process for breast cancer involves a mammogram and in the event of abnormal cells are identified, a needle biopsy is the next
Research conducted at King’s College London has revealed how blood inflammation affects the birth and death of brain cells, potentially offering insight for new treatment targets for antidepressants. Mounting evidence points to high levels of inflammation as vital biological abnormality leading to depression in at least one third of patients. Although, the new study offers
Research at the University of York found evidence to suggest that genes are controlled by ‘nano footballs’, as the structures bear a strong resemblance to footballs but 10 million times smaller than the average ball. By placing tiny glowing probes on transcription factors, special chemicals inside cells which control whether a gene is switched ‘on’
The human brain is protected by the near impermeable blood brain barrier, often referred to as a fortress that protects the brain but also prevents the treatment of brain diseases, including brain tumours. Dr Zaynah Maherally and her team at University of Portsmouth have developed a model that mimics this barrier, with has helped in
The Fluad flu vaccine, produced by Seqirus, has been approved by the MHRA for use at the start of 2018. Further data has also been released to back up the decision, which shows that a potential 1,700 lives could be saved through its use. The data suggested the vaccine was effective at protecting adults over