Genomics England has successfully completed the first phase of its study assessing plasma samples and potential of liquid biopsy. The research, conducted in collaboration with Inivata and Thermo Fisher Scientific, analysed around 200 blood plasma samples donated by participants of the 100,000 Genomes Project. The results showed that the plasma samples were of a high
The bacterium, Porphyromonas gingivalis, which is involved in periodontitis, the most serious form of gum disease. These new findings underscore the importance of good dental hygiene as scientists seek ways to better control this common bacterial infection. “Oral hygiene is very important throughout our life, not only for having a beautiful smile but also to decrease
Cardiff University plans to launch the new Medicines Discovery Institute, increasing the development of new drugs for mental health such as anxiety and central nervous system conditions. The institute, which is part funded by the Welsh Government, the Higher Education Funding Council for Wales and the European Regional Development Fund, will develop novel medications to
Scientists have developed and tested a vaccine that they say could be used to treat chronic pain caused by osteoarthritis. In a collaboration by the Jenner Institute and the Kennedy Institute of Rheumatology at the University of Oxford, researchers have developed a virus-like particle vaccine able to trigger the immune system to produce antibodies to
As part of a new project to sequence specific parts of a genome from 50k UK biobanks, new genetic data becomes available to the global health research community. Generated at the Regeneron Genetics Center, the data was gathered as part of a large-scale collaboration between UK Biobank, GSK and Regeneron and according to the latter, it has
Swiss researchers have been studying people with a rare and unusual condition called broken heart syndrome. This weakening and failing of the heart happens suddenly, often after a stressful or emotional event such as bereavement. It is little understood but the work in the European Heart Journal suggests the mind’s response to stress plays a part. Also
A British scientist has developed innovative technology that is able to deliver drugs deep into the brain, which could aid treatment of neurological diseases including Parkinson’s and cancer. The technology was designed by Steven Gill, a professor of neurosurgery at the University of Bristol, and has shown encouraging results in its first controlled clinical trial.
The first map of great whites sharks’ DNA has revealed “mutations” that protect the animals against cancer and other illnesses. Scientists hope that more research could help apply the findings to treating age-related illnesses in humans, as the great white’s ability to repair its own DNA has evolved in ways ours hasn’t. Unstable genes in
The research led by scientists at the MRC Toxicology Unit based in Leister suggests that by analysing levels of DNA in the blood, the early detection of lung cancer could be improved. Published in the journal Disease Models and Mechanisms, the study found that in preliminary tests using mice a blood test could measure the circulating levels
First child with acute lymphoblastic leukaemia (ALL) receives CAR-T therapy on the NHS, treatment to be made available to adult patients.
There has been with two significant developments in the use of CAR-T therapies, marking a historic time for blood cancer treatments, as recent headlines announced that the first child with ALL had successfully received CAR-T therapy on the NHS. CAR-T therapies are a revolutionary treatment that take samples of immune cells from the patient and genetically modify