Overview

Reference Number: JO-2009-454120
Director of Research Immunology
Rate: Negotiable
Job Type: Permanent
Location: Cambridge

Director of Research Immunology
Cambridge
Competitive package

An innovative Biotechnology business focussing on antibody technologies are looking to recruit a Director of Research Immunology. This individual will be leading the team responsible for the development of new in vivo models & capabilities to drive the progression of projects within the Immunology portfolio. In this role, youll also play a key role with the department leadership team in developing strategy in IO and auto-immune disease.

Youll be a subject matter expert for the team and company more broadly, maintaining an in-depth understanding of fundamentals of auto-immune disease, immunology, immune-oncology & tumour biology

Its expected youll be able to communicate with and successfully influence senior level management, executives & stakeholders at all levels as well as leading and developing a team of talented scientists, bioinformaticians & technical experts.

Responsibilities:
Lead a team of scientists
o Lead the in vivo effort which includes being the oncology project license holder and Lead the team to develop new models and deliver preclinical efficacy in vivo proof of concept and evaluate mechanism of action in in vivo models
o Demonstrate the ability to enthuse and motivate a multi-disciplinary team
Lead projects and multi-functional teams
o Lead capability development and the assessment and validation of novel targets in the chosen research areas.
o Work with a multidisciplinary team to plan and execute preclinical in vitro and in vivo experiments supporting biological and mechanistic understanding of our molecules.
o Write patents and contribute to the generation of regulatory documentation (e.g. in support of molecules progressing to clinical development).
o Identify opportunities and lead the authorship of peer reviewed manuscripts and presentation of original work at scientific conferences and symposia
o Work effectively with external groups including collaborators and CRO
o Critically analyse, interpret, and report experimental results, draw appropriate conclusions and design next experimental steps driving project progression.
Active presentation of findings at internal and external meetings

Requirements
PhD in Immunology, Cancer Biology or equivalent industrial experience
Demonstrable leadership experience
In depth knowledge of in vivo oncology models
Good publication record
Extensive experience of supporting late stage antibody discovery into early stage development
In depth knowledge & understanding of pre-clinical research objectives to drive project progression in IO & auto-immune disease
Demonstrable track record of successful research supported by publications (peer reviewed publications, oral presentations, posters & patent filings)
Strong basis in the fundamentals of immunology and auto-immune disease
Strong knowledge of oncology especially immune-oncology
Ability to multitask and work to competing deadlines
In depth knowledge of antibody drug development

This role will offer some home working but will require an individual to be based in Cambridge predominantly. As a result the organisation offer a competitive relocation package and further assistance if needed.

If you would be interested in hearing more please apply on line. Any queries can be directed to Kimberley on 07900981267.

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